ALX1 Antibody
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								中文名稱:ALX1兔多克隆抗體
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								貨號:CSB-PA624031LA01HU
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								規(guī)格:¥440
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								圖片:- 
														
														Western Blot
 Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate
 All lanes: ALX1 antibody at 3μg/ml
 Secondary
 Goat polyclonal to rabbit IgG at 1/50000 dilution
 Predicted band size: 37 kDa
 Observed band size: 37 kDa
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														Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA624031LA01HU at dilution of 1:100
 
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								其他:
產(chǎn)品詳情
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											產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) ALX1 Polyclonal antibody
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											Uniprot No.:
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											基因名:ALX1
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											別名:ALX homeobox 1 antibody; ALX homeobox protein 1 antibody; ALX1 antibody; ALX1_HUMAN antibody; CART 1 antibody; CART-1 antibody; CART1 antibody; Cartilage homeoprotein 1 antibody; Cartilage paired class homeoprotein 1 antibody; FND3 antibody
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											宿主:Rabbit
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											反應(yīng)種屬:Human
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											免疫原:Recombinant Human ALX homeobox protein 1 protein (10-304AA)
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											免疫原種屬:Homo sapiens (Human)
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											標(biāo)記方式:Non-conjugated本頁面中的產(chǎn)品,ALX1 Antibody (CSB-PA624031LA01HU),的標(biāo)記方式是Non-conjugated。對于ALX1 Antibody,我們還提供其他標(biāo)記。見下表: 
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											克隆類型:Polyclonal
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											抗體亞型:IgG
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											純化方式:>95%, Protein G purified
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											濃度:It differs from different batches. Please contact us to confirm it.
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											保存緩沖液:Preservative: 0.03% Proclin 300
 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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											產(chǎn)品提供形式:Liquid
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											應(yīng)用范圍:ELISA, WB, IHC
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											推薦稀釋比:Application Recommended Dilution WB 1:500-1:5000 IHC 1:20-1:200 
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											Protocols:
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											儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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											貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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											用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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											功能:Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1.
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											基因功能參考文獻(xiàn):- According to our analysis, three proteins, namely aristaless-like homeobox1 isoform X1 (ALX1), major histocompatibility complex polypeptide-related sequence A (MICA), and uncharacterized protein C14orf105 isoform X12 were found to be potential markers for Opisthorchis viverrini (OV)- infection, as they were predominantly found in all OV-infected groups PMID: 29936472
- Our study concludes that the splice site variant identified in the ALX1 gene causes mild form of Frontonasal dysplasia. PMID: 27324866
- we identify critical roles of ALX1 in lung cancer development and progression PMID: 26722397
- Knockdown of the CART1 gene significantly inhibited cell invasion and proliferation and induce cell cycle arrest in S phase. PMID: 27053613
- we found that depletion of ALX1 caused a dramatic cell cycle arrest, followed by massive apoptotic cell death, and eventually resulted in a significant decrease in migration and invasion of the osteosarcoma cell line studied. PMID: 25736924
- hypermethylation of HIST1H4F, PCDHGB6, NPBWR1, ALX1, and HOXA9 was significantly associated with shorter survival in stage 1 Non-small-cell lung cancer PMID: 24081945
- ALX1 upregulated expression of the key EMT regulator Snail (SNAI1) and that it mediated EMT activation and cell invasion by ALX1. PMID: 23288509
- Disruption of CART1 (ALX1) causes extreme microphthalmia and severe facial clefting. PMID: 20451171
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											相關(guān)疾?。?/div>Frontonasal dysplasia 3 (FND3)亞細(xì)胞定位:Nucleus.蛋白家族:Paired homeobox family組織特異性:Cartilage and cervix tissue.數(shù)據(jù)庫鏈接:
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