搡老女人多毛老妇女中国,日韩亚洲欧美中文高清在线,人妻少妇一区二区三区,色妞色综合久久夜夜,日本熟妇xxxx

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CDAN1 Antibody

CDAN1 Antibody

  • 中文名稱：
    CDAN1兔多克隆抗體
  • 貨號：
    CSB-PA004978GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    CDAN1
  • 別名：
    CDA1 antibody; CDAI antibody; CDAN1 antibody; CDAN1_HUMAN antibody; Codanin antibody; Codanin-1 antibody; Codanin1 antibody; PRO1295 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Human CDAN1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    May act as a negative regulator of ASF1 in chromatin assembly.
  • 基因功能參考文獻：
    1. Mutation in CDAN1 gene is associated with congenital dyserythropoietic anemia. PMID: 29031773
    2. The missense substitution in CDAN1, C15ORF41, encodes a novel restriction endonuclease in congenital dyserythropoietic anemia type I. PMID: 23716552
    3. The proband with congenital dyserythropoietic anemia Iota in the first family was a compound heterozygote of CDAN1 with mutation IVS-12+2T>C and c. 3389C>T. PMID: 24196372
    4. The authors propose that Codanin-1 acts as a negative regulator of Asf1 function in chromatin assembly. PMID: 22407294
    5. A link between mutant codanin-1 and the aberrant localization of HP1 alpha is supported by the finding that codanin-1 can be coimmunoprecipitated by anti-HP1 alpha antibodies erythroblasts from patients with congenital dyserythropoietic anemia type 1. PMID: 21364188
    6. Congenital dyserythropoietic anemia type I is caused by mutations in codanin-1 PMID: 12434312
    7. codanin-1 may play a role in the development of the skeleton. PMID: 16767397
    8. This second case of retinal angioid streaks in CDA I reports a patient homozygous for the Arg1042Trp mutation in codanin-1. PMID: 18081704
    9. Congenital dyserythropoietic anemia I (CDA I) is a well-defined entity within the heterogeneous group of the CDAN1 family; here it is associated with mutations in a Chinese family. PMID: 18575862
    10. Data suggest that codanin-1 is a cell cycle-regulated protein active in the S phase. PMID: 19336738

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Anemia, congenital dyserythropoietic, 1A (CDAN1A)
  • 亞細胞定位：
    Cytoplasm. Nucleus. Membrane; Multi-pass membrane protein. Note=Mainly detected as a cytoplasmic protein.
  • 組織特異性：
    Ubiquitously expressed. Isoform 3 is not found in erythroid cells.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 1713

    OMIM: 224120

    KEGG: hsa:146059

    STRING: 9606.ENSP00000348564

    UniGene: Hs.599232