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ELAVL2 Antibody

  • 中文名稱：
    ELAVL2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA002900
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of Jurkat cells using Hel-N1 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    ELAVL2
  • 別名：
    ELAV like neuron specific RNA binding protein 2 antibody; ELAV like Neuronal Protein 1 antibody; ELAV like Protein 2 antibody; ELAV-like neuronal protein 1 antibody; ELAV-like protein 2 antibody; ELAV2_HUMAN antibody; ELAVL2 antibody; HEL-N1 antibody; HELN1 antibody; HU Antigen B antibody; Hu-antigen B antibody; HuB antibody; Nervous System Specific RNA Binding Protein MelN1 antibody; Nervous system-specific RNA-binding protein Hel-N1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human Hel-N1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    RNA-binding protein that binds to the 3' untranslated region (3'UTR) of target mRNAs. Seems to recognize a GAAA motif. Can bind to its own 3'UTR, the FOS 3'UTR and the ID 3'UTR.
  • 基因功能參考文獻(xiàn)：
    1. ELAVL2-regulated co-expression networks are also enriched for neurodevelopmental and synaptic genes, and include genes with human-specific patterns of expression in the frontal pole. Together, these data suggest that ELAVL2 regulation of transcript expression is critical for neuronal function and clinically relevant to autism PMID: 27260404
    2. The 17 proteins that interact with 10 or more other proteins (P < 0.05, FDR < 0.05) were identified as the hub proteins. PMID: 26366417
    3. Tests for gene-environment interaction between these 33 genes and maternal smoking found evidence for interaction with two additional genes: GRID2 and ELAVL2 among European mothers PMID: 23512105
    4. the mutually antagonistic action of two RNA-binding proteins, Hu and hnRNP K, control the timing of the switch from proliferation to neuronal differentiation through the post-transcriptional regulation of p21 mRNA PMID: 15671036
    5. increased level of mRNA transcripts detected in Small Cell Lung Cancer patients PMID: 18607064

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  • 蛋白家族：
    RRM elav family
  • 組織特異性：
    Brain; neural-specific.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 3313

    OMIM: 601673

    KEGG: hsa:1993

    STRING: 9606.ENSP00000369460

    UniGene: Hs.166109