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  4. FOXI1 Antibody

FOXI1 Antibody

  • 中文名稱：
    FOXI1兔多克隆抗體
  • 貨號：
    CSB-PA622520LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: HepG2 whole cell lysate, A549 whole cell lysate
      All lanes: FOXI1 antibody at 3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 41, 31 kDa
      Observed band size: 41 kDa
    • Immunofluorescent analysis of Hela cells using CSB-PA622520LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) FOXI1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FOXI1
  • 別名：
    FKH10 antibody; FKHL10 antibody; Forkhead (Drosophila) like 10 antibody; Forkhead box I1 antibody; Forkhead box protein I1 antibody; Forkhead like 10 antibody; Forkhead related activator 6 antibody; Forkhead related transcription factor 6 antibody; Forkhead-related protein FKHL10 antibody; Forkhead-related transcription factor 6 antibody; FOXI1 antibody; FOXI1_HUMAN antibody; FREAC 6 antibody; FREAC-6 antibody; FREAC6 antibody; Hepatocyte nuclear factor 3 forkhead homolog 3 antibody; HFH 3 antibody; HFH-3 antibody; HFH3 antibody; HNF 3/fork head homolog 3 antibody; HNF-3 fork-head homolog 3 antibody; HNF-3/fork-head homolog 3 antibody; Human HNF-3 fork-head homolog-3 HFH-3 mRNA complete cds antibody; MGC34197 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Forkhead box protein I1 protein (183-343AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，F(xiàn)OXI1 Antibody (CSB-PA622520LA01HU)，的標(biāo)記方式是Non-conjugated。對于FOXI1 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA622520LB01HU FOXI1 Antibody, HRP conjugated ELISA
    FITC CSB-PA622520LC01HU FOXI1 Antibody, FITC conjugated
    Biotin CSB-PA622520LD01HU FOXI1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules.
  • 基因功能參考文獻：
    1. study reveals that Foxi1/miR-491-5p/Wnt3a/beta-catenin signaling is critical in the progression of GC. Targeting the pathway described in this study may open up new prospects to restrict the progression of gastric cancer PMID: 28358374
    2. We found no evidence for a significant association between mutations of KCNJ10 and FOXI1 with SLC26A4 in Pendred syndrome/enlarged vestibular aqueducts. PMID: 23965030
    3. No FOXI1 mutations were present in bilateral deafness patients with inner ear malformation. PMID: 22412181
    4. SLC26A4, FOXI1 and KCNJ10 are not major determinants in unilateral deafness and enlarged vestibular aqueduct PMID: 20621367
    5. C/EBP alpha and HNF-3 gamma cooperatively regulate CYP3A4 expression in hepatic cells by a mechanism that probably involves chromatin remodeling. PMID: 12695546
    6. Data suggestthat Foxi1 is necessary for expression of at least four subunits in three different epithelia and most likely is a major determinant for proper assembly of a functional vacuolar H(+)-ATPase complex at these locations. PMID: 19214237

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  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Expressed in kidney.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 3815

    OMIM: 601093

    KEGG: hsa:2299

    STRING: 9606.ENSP00000304286

    UniGene: Hs.87236