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HFM1 Antibody

  • 中文名稱：
    HFM1兔多克隆抗體
  • 貨號：
    CSB-PA010325LA01HU
  • 規(guī)格：
    ￥880
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA010325LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA010325LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HFM1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HFM1
  • 別名：
    HFM1 antibody; SEC3D1Probable ATP-dependent DNA helicase HFM1 antibody; EC 3.6.4.12 antibody; SEC63 domain-containing protein 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Probable ATP-dependent DNA helicase HFM1 protein (121-420AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，HFM1 Antibody (CSB-PA010325LA01HU)，的標記方式是Non-conjugated。對于HFM1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA010325LB01HU HFM1 Antibody, HRP conjugated ELISA
    FITC CSB-PA010325LC01HU HFM1 Antibody, FITC conjugated
    Biotin CSB-PA010325LD01HU HFM1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Required for crossover formation and complete synapsis of homologous chromosomes during meiosis.
  • 基因功能參考文獻：
    1. Data suggest that HFM1 gene might be associated with primary ovarian insufficiency in Chinese population. PMID: 26679638
    2. Exome sequencing of two Chinese sisters with primary ovarian insufficiency and their parents identified a shared compound heterozygous mutation in a meiotic gene, HFM1, which encodes a protein necessary for homologous recombination of chromosomes. PMID: 24597873
    3. hHFM1 is the evolutionally conserved putative human DNA helicase, which may function as a modulator for genome integrity in germ-line tissues. PMID: 17286053
  • 相關疾病：
    Premature ovarian failure 9 (POF9)
  • 蛋白家族：
    Helicase family, SKI2 subfamily
  • 組織特異性：
    Preferentially expressed in testis and ovary.
  • 數據庫鏈接：

    HGNC: 20193

    OMIM: 615684

    KEGG: hsa:164045

    STRING: 9606.ENSP00000359454

    UniGene: Hs.454818