MILR1 Antibody, Biotin conjugated
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								中文名稱:MILR1兔多克隆抗體, Biotin偶聯(lián)
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								貨號:CSB-PA801819LD01HU
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								規(guī)格:¥880
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								其他:
產(chǎn)品詳情
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											產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) MILR1 Polyclonal antibody
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											Uniprot No.:
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											基因名:MILR1
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											別名:Allergin-1 antibody; Allergy inhibitory receptor 1 antibody; C17orf60 antibody; Mast cell antigen 32 antibody; Mast cell immunoglobulin-like receptor 1 antibody; MCA-32 antibody; MCA32 antibody; MILR1 antibody; MILR1_HUMAN antibody; Probable mast cell antigen 32 homolog antibody
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											宿主:Rabbit
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											反應(yīng)種屬:Human
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											免疫原:Recombinant Human Allergin-1 protein (249-343AA)
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											免疫原種屬:Homo sapiens (Human)
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											標記方式:Biotin
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											克隆類型:Polyclonal
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											抗體亞型:IgG
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											純化方式:>95%, Protein G purified
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											濃度:It differs from different batches. Please contact us to confirm it.
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											保存緩沖液:Preservative: 0.03% Proclin 300
 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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											產(chǎn)品提供形式:Liquid
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											應(yīng)用范圍:ELISA
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											Protocols:
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											儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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											貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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											用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關(guān)產(chǎn)品
靶點詳情
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											功能:Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction.
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											基因功能參考文獻:- Data indicate that the rs6504230 polymorphism affects MILR1 (mast cell immunoglobulin-like receptor 1; synonyms, Allergin-1) expression levels, leading to a susceptibility to producing specific IgE antibodies against common allergens. PMID: 25007884
- Allergin-1S1, a splicing isoform of Allergin-1, is predominantly expressed on human primary MC in both bronchoalveolar lavage fluid and nasal scratching specimens. Moreover, Allergin-1S1 inhibits IgE-mediated activation from human primary MC in BAL fluid. PMID: 24116093
- It is a immunoglobulin-like receptor which regulates the activation of mast cell.(review) PMID: 24552759
 
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											亞細胞定位:Cell membrane; Single-pass type I membrane protein.
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											組織特異性:Expressed in myeloid cells (dendritic cells, macrophages and neutrophils, weak expression on B-cells but not in T-cells or natural killer cells), peripheral blood basophils and mast cells (at protein level).
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											數(shù)據(jù)庫鏈接:
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