NXN Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q6DKJ4
基因名：

NXN
別名：

FLJ12614 antibody; NRX antibody; nucleoredoxin 1 antibody; Nucleoredoxin antibody; Nxn antibody; NXN_HUMAN antibody; OTTHUMP00000115356 antibody; TRG 4 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human NXN
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A).
基因功能參考文獻：
1. identified nucleoredoxin as an interaction partner of Sec63; characterized this interaction; Sec63 is linked to the Wnt signaling pathways and this interaction may be the reason why mutations in SEC63 can lead to polycystic liver disease PMID: 21251912
2. Nucleoredoxin is a novel thioredoxin family member involved in cell growth and differentiation [review] PMID: 17567240
亞細胞定位：

Cytoplasm, cytosol. Nucleus.
蛋白家族：

Nucleoredoxin family
數(shù)據(jù)庫鏈接：

HGNC: 18008

OMIM: 612895

KEGG: hsa:64359

STRING: 9606.ENSP00000337443

UniGene: Hs.527989