PIGK Antibody, FITC conjugated

說(shuō)明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) PIGK Polyclonal antibody
Uniprot No.：

Q92643
基因名：

PIGK
別名：

PIGK antibody; GPI8 antibody; GPI-anchor transamidase antibody; GPI transamidase antibody; EC 3.-.-.- antibody; GPI8 homolog antibody; hGPI8 antibody; Phosphatidylinositol-glycan biosynthesis class K protein antibody; PIG-K antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human GPI-anchor transamidase protein (91-293AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.
基因功能參考文獻(xiàn)：
1. Report firstly demonstrated that inadequate protein-glycosylphosphatidylinositol anchoring caused by suppression of PIGK might affect the expression or function of some glycosylphosphatidylinositol-anchored proteins associated with tyrosinase activity. PMID: 27919619
2. Our results demonstrate, for the first time, a link between the SNP 1048575 and low PIGK expression in CRC/HCC patients and also suggest a possible association between altered PIGK expression and disease susceptibility. PMID: 22824918
3. GPI8 and PIG-T form a functionally important intermolecular disulfide bridge PMID: 12582175
亞細(xì)胞定位：

Endoplasmic reticulum membrane; Single-pass type I membrane protein.
蛋白家族：

Peptidase C13 family
數(shù)據(jù)庫(kù)鏈接：

HGNC: 8965

OMIM: 605087

KEGG: hsa:10026

STRING: 9606.ENSP00000359848

UniGene: Hs.178305