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POLE2 Antibody

  • 中文名稱：
    POLE2兔多克隆抗體
  • 貨號：
    CSB-PA004689
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of Jurkat cells using DNA pol ε B Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    DNA polymerase epsilon subunit 2 antibody; DNA polymerase epsilon subunit B antibody; DNA polymerase II subunit 2 antibody; DPE 2 antibody; DPE2 antibody; DPOE2_HUMAN antibody; POLE 2 antibody; POLE2 antibody; Polymerase (DNA directed) epsilon 2 (p59 subunit) antibody; Polymerase (DNA directed) epsilon 2 antibody; polymerase (DNA directed); epsilon 2; accessory subunit antibody; Polymerase; DNA; epsilon-2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human DNA pol ε B.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Accessory component of the DNA polymerase epsilon complex. Participates in DNA repair and in chromosomal DNA replication.
  • 基因功能參考文獻(xiàn)：
    1. found that mutations occurred in POLE2 in 5 out of 16 cases of human colon cancer examined. PMID: 20065316
    2. The solution structure of the N-terminal domain of human DNA polymerase epsilon subunit B revealed a domain that consists of a left-handed superhelical bundle. PMID: 18676977
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    DNA polymerase epsilon subunit B family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9178

    OMIM: 602670

    KEGG: hsa:5427

    STRING: 9606.ENSP00000216367

    UniGene: Hs.162777