RASGEF1B Antibody, HRP conjugated

說(shuō)明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) RASGEF1B Polyclonal antibody
Uniprot No.：

Q0VAM2
基因名：

RASGEF1B
別名：

FLJ31695 antibody; GPI gamma-4 antibody; GPIG4 antibody; MGC46251 antibody; Ras-GEF domain-containing family member 1B antibody; RasGEF domain family member 1B antibody; RASGEF1B antibody; RGF1B_HUMAN antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Ras-GEF domain-containing family member 1B protein (1-300AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro).
基因功能參考文獻(xiàn)：
1. We show that knockdown of the expression of mcircRasGEF1B reduces LPS-induced ICAM-1 expression. Additionally, we demonstrate that mcircRasGEF1B regulates the stability of mature ICAM-1 mRNAs. PMID: 27362560
2. As an addition to PRKG2 and RASGEFIB genes, we propose to include BMP3 gene as the principal determinant of the observed common phenotype. PMID: 22303795
3. Mutation of the Ser39 in Rap1 changed the specificity and allowed the nucleotide exchange of Rap1(S39F) to be stimulated by RasGEF1B PMID: 19645719
亞細(xì)胞定位：

Early endosome. Late endosome. Midbody.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 24881

OMIM: 614532

KEGG: hsa:153020

STRING: 9606.ENSP00000264400

UniGene: Hs.591696