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RGL2 Antibody, Biotin conjugated

  • 中文名稱：
    RGL2兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA019625LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RGL2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    GDS related protein antibody; HKE1.5 antibody; KE1.5 antibody; RAB2L antibody; Ral guanine nucleotide dissociation stimulator-like 2 antibody; RalGDS-like 2 antibody; RalGDS-like factor antibody; Ras-associated protein RAB2L antibody; RGL2 antibody; RGL2_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Ral guanine nucleotide dissociation stimulator-like 2 protein (145-328AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro.
  • 基因功能參考文獻(xiàn)：
    1. SAMD9, an IFN-gamma-responsive protein, interacts with RGL2 to diminish the expression of EGR1, a protein of direct relevance to the pathogenesis of ectopic calcification and inflammation. PMID: 21160498
    2. Rgl2 and RalB both localized to the leading edge, and this localization of RalB was dependent on endogenous Rgl2 expression. PMID: 20801877
    3. RGL2 is phosphorylated by PKA and phosphorylation reduces the ability of RGL2 to bind H-Ras. results of the present study indicate that Ras may distinguish between the different RalGDS family members by their phosphorylation by PKA. PMID: 18540861
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 9769

    OMIM: 602306

    KEGG: hsa:5863

    STRING: 9606.ENSP00000420211

    UniGene: Hs.509622