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TBKBP1 Antibody, FITC conjugated

  • 中文名稱：
    TBKBP1兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA023233LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TBKBP1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    KIAA0775 antibody; ProSAPiP2 antibody; SINTBAD antibody; TANK binding kinase 1 binding protein 1 antibody; TANK-binding kinase 1-binding protein 1 antibody; TBK1 binding protein 1 antibody; TBK1-binding protein 1 antibody; TBKB1_HUMAN antibody; Tbkbp1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human TANK-binding kinase 1-binding protein 1 protein (327-427AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.
  • 基因功能參考文獻(xiàn)：
    1. The two selected single nucleotide polymorphisms (SNPs) in TBKBP1 show no relationship with the clinical outcomes. None of the 12 SNPs is related to mSASSS. PMID: 25494292
    2. TBKBP1 is associated with the severity of ankylosing spondylitis in the Chinese Han population PMID: 23637848
    3. Studies show that three proteins expressed in HEK-293T cells (NAP1, TANK and TBKBP1) interact with TBK1. PMID: 23286385
    4. results suggest that efficient signal transduction upon viral infection requires SINTBAD, TANK and NAP1 because they link TBK1 and IKKi to virus-activated signalling cascades PMID: 17568778
  • 組織特異性：
    Detected in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, muscle, heart, brain and at low levels in thymus.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 30140

    OMIM: 608476

    KEGG: hsa:9755

    STRING: 9606.ENSP00000354777

    UniGene: Hs.94790