TRIM38 Antibody
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								中文名稱:TRIM38兔多克隆抗體
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								貨號(hào):CSB-PA006550
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								規(guī)格:¥1090
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								圖片:
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								其他:
產(chǎn)品詳情
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											Uniprot No.:
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											基因名:TRIM38
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											別名:TRIM38 antibody; RNF15 antibody; RORET antibody; E3 ubiquitin-protein ligase TRIM38 antibody; EC 2.3.2.27 antibody; RING finger protein 15 antibody; RING-type E3 ubiquitin transferase TRIM38 antibody; Tripartite motif-containing protein 38 antibody; Zinc finger protein RoRet antibody
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											宿主:Rabbit
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											反應(yīng)種屬:Human,Mouse
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											免疫原:Synthesized peptide derived from the Internal region of Human RNF15.
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											免疫原種屬:Homo sapiens (Human)
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											標(biāo)記方式:Non-conjugated
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											抗體亞型:IgG
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											純化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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											濃度:It differs from different batches. Please contact us to confirm it.
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											保存緩沖液:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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											產(chǎn)品提供形式:Liquid
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											應(yīng)用范圍:WB, ELISA
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											推薦稀釋比:Application Recommended Dilution WB 1:500-1:2000 ELISA 1:40000 
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											Protocols:
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											儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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											貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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											用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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											功能:E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling.
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											基因功能參考文獻(xiàn):- Data suggest that mRNA/protein levels of NLRP6 are down-regulated in synovial tissues and synoviocytes of rheumatoid arthritis (RA) patients compared to osteoarthritis patients; NLRP6 provides docking site to facilitate interaction between TAB2/3 and TRIM38 in RA synoviocytes in response to TNFalpha. (NLRP6 = ; TAB2/3 = transforming growth factor-b-activated kinase 1-binding protein 2/3; TRIM38 = tripartite motif 38) PMID: 28295271
- TRIM38 may act as a novel negative regulator for TLR3-mediated type I interferon signaling by targeting TRIF for degradation PMID: 23056470
- NF-kappaB is activated in response to TRIM38. PMID: 21789858
- Enterovirus 71 infection induces degradation of TRIM38. PMID: 21306652
 
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											組織特異性:Ubiquitous.
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											數(shù)據(jù)庫(kù)鏈接:
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