WDFY4 Antibody, Biotin conjugated

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) WDFY4 Polyclonal antibody
Uniprot No.：

Q6ZS81
基因名：

WDFY4
別名：

WDFY4 antibody; C10orf64 antibody; KIAA1607WD repeat- and FYVE domain-containing protein 4 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human WD repeat- and FYVE domain-containing protein 4 protein (1-322AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy.
基因功能參考文獻(xiàn)：
1. A significantly increased risk for RA associated with the WDFY4 rs7097397 AG genotype. PMID: 24549174
2. rs877819 SNP in WDFY4 may be associated with systemic lupus erythematosus by reduced binding of YY1 and downregulating WDFY4 expression. PMID: 22972472
3. Genetic variants in ETS1 and WDFY4 were found to be associated with systemic lupus erythematosus, in the Asian population studied. PMID: 20169177
亞細(xì)胞定位：

Early endosome. Endoplasmic reticulum.
數(shù)據(jù)庫鏈接：

HGNC: 29323

OMIM: 613316

KEGG: hsa:57705

STRING: 9606.ENSP00000320563

UniGene: Hs.287379